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Research
1.
Spirocercosis in stray dogs of Chittagong
metropolitan area of Bangladesh: an
epidemiological and pathological investigation -
Shubhagata Das, Md Abdul Alim, Mohammad Mahmudul
Hassan, Suchandan Sikder, Muraduzzaman, Md
Masuduzzaman
Vet World. 2011; 4(11): 485-491
doi: 10.5455/vetworld.2011.485-491
Abstract
A total of sixty adult stray dogs (32 male and 28
female) randomly captured from different locality
of Chittagong metropolitan area were euthanized
during the period of May 2010 to January 2011. The
dogs were necropsized to observe the presence of
Spirocerca lupi in their oesophagus producing
characteristic nodular lesions. The associated
haematological changes were also determined.
Twenty four (40%) of the captured dogs were
positive (40.62 % male and 39.28 % female) for
spirocercosis having oesophageal nodular lesions.
One to three broad based nodular lesions with an
average diameter of 2.104±0.139 cm were observed
in the caudal oesophagus of spirocerca positive
dogs. Minimum 1 and maximum 12 worms found
harboring in each nodule with an average number of
3.75± 0.686. The association between the
oesophageal nodular lesions and body condition of
the dogs was inconclusive and location- wise
prevalence was also not clear. Anaemia was
observed in infected dogs with significant
reduction in ESR values and MCHC%. Leukocytosis,
particularly neutrophilia was common in infected
dogs in comparison to the non-infected.
Histopathology revealed extensive fibrous tissue
proliferation around the adult worms in most of
the nodular lesions with large numbers of newly
formed blood vessels resembling granulation
tissues. A considerable degree of fibroplasia was
evident with predominant accumulation of
fibroblasts and irregular layers collagen fibers
in mature nodules. Accumulation of large numbers
of neutrophil was common in nodular lesions,
whereas, infiltration of lymphoplasmacytic cells
also found in some cases. One lesion showed
evidence of fibrosarcoma characterized by
proliferation of undifferentiated atypical
fibroblasts having abnormal mitotic figures.
Keywords: Fibrosarcoma, Histopathology,
Haematology, Nodule, Prevalence, Stray dogs,
Spirocercosis, Parasite
